Finasteride, brand-name Propecia or Proscar among others, is a synthetic anti-androgen that acts primarily through the inhibition of the 5-AR (5-alpha-reductase) enzyme, which is primarily responsible for converting testosterone into DHT (di-hydro-testosterone). 5-AR reduces the 4,5 double bond of testosterone which converts it into the biologically-active DHT hormone, which is three times more potent than testosterone; production of DHT via conversion from testosterone takes place primarily in the hair follicles, prostate, testicles, and adrenal glands. DHT is not converted to estradiol via aromatase.
DHT is the primary factor implemented in common male pattern baldness and occasionally is the primary factor in female hair loss. DHT plays a role in the development and progression of benign prostatic hyperplasia (BPH), as well as in prostate cancer, via enlargement of the prostate gland. Normal growth of prostate cells and prostate cell differentiation also depends heavily on DHT.
LIQUID FINASTERIDE (propecia) 60ml @ 5mg/ml