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MGF (mechano growth factctor) IGF-1Ec is a naturally occuring tissue growth and repair factor expressed by mechanically overloaded muscle fibers.
Loss of muscle mass in old age and in certain diseases is associated with an impaired ability to express MGF.
► The ability to produce MGF declines with age, and this is commensurate with the decline in circulating GH levels.
► MGF has been shown to boost muscle mass by improving the ability of wasted tissue to grow.
► MGF has been shown to improve the ability of wasted tissue to grow.
► MGF has been shown to activate muscle stem cells.
► MGF has been shown to increase the upregulation of protein synthesis.
► MGF induces rapid muscle hypertrophy.
► MGF has considerable potential as a generic means of treating muscle cachexia.
► Mechano Growth Factor (MGF) targets skeletal tissue, and promotes muscle growth by repairing the damaged tissue and upregulating protein synthesis.
Mechano Growth Factor (MGF) also known as IGF-1Ec is a growth factor/repair factor that is derived from exercised or damaged muscle tissue. MGF has been shown to boost muscle mass by improving the ability of wasted tissue to grow and improve itself by activating muscle stem cells and increasing the upregulation of protein synthesis. MGF is a part of the IGF family, but, in the case of MGF, this part of the peptide acts as a separate growth factor involved in initiating muscle satellite (stem) cell activation in addition to its IGF-Ireceptor domain which increases protein synthesis, and hence improves muscle mass.